METHOD OF DECREASING CHROMATOGRAPHIC COLUMN PLUGGING BY ADDITION OF WATER TO THE CARRIER LIQUID

摘要

METHOD OF DECREASING CHROMATOGRAPHIC COLUMN PLUGGING BY ADDITION OF WATER TO THE CARRIER LIQUID In the liquid chromatographic analysis of a sample containing two or more constituents which are chromatographically separable using an aqueous ether carrier liquid, an effective amount of water is added to the chromatographic carrier liquid thereby increasing the efficiency of the chromatographic separation and decreasing the incidence of chromatographic column plugging. In a preferred embodiment, addition of a small amount of water to a tetrahydrofuran carrier liquid results in substantial improvement in the analysis of a sulfuric acid alkylation catalyst wherein a sample containing sulfuric acid and other chromatographically separatable organic materials is separated in order to measure the relative proportions of sulfuric acid and hydrocarbon or other materials within the sample.