| 发明名称 |
Preparation of therapeutic compounds |
| 摘要 |
A process is disclosed for preparing arylpropionic acids of formula Ar-CH(CH3)-COOH, by reacting an aryl Grignard reagent with a metal pyruvate or with a pyruvamide, to form a hydroxy acid of formula Ar-C(OH)(CH3)-COOH or its amide, and converting the acid or amide to the product.
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| 申请公布号 |
US4188491(A) |
申请公布日期 |
1980.02.12 |
| 申请号 |
US19780889644 |
申请日期 |
1978.03.24 |
| 申请人 |
BOOTS CO LTD THE |
发明人 |
NICHOLSON, JOHN S;TURNER, JOHN L |
| 分类号 |
C07C51/367;C07C51/377;C07C57/58;C07D207/08;C07D207/32;C07D207/337;C07D211/34;C07D213/54;C07D295/185;C07D307/54;C07D317/72;C07D333/24;(IPC1-7):C07C63/33 |
主分类号 |
C07C51/367 |
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