发明名称 NOVEL GLUCOPYRANOSE DERIVATIVE, PRODUCTION THEREOF AND MEDICINE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT
摘要 NEW MATERIAL:A compound expressed by formula I [R represents H, OH or 1-4C alkoxy; R<1> represents single bond or 2-20C oxycarbonylalkyl; R<2> and R<6> represent H, formulae II or III (R<10> represents H, 1-7C alkyl, halogen atom, etc.; m is 1-3), etc.; R<3> represents 1-20C alkylene; R<4> represents H, formulae IV or V (R<11> represents H, 1-7C alkyl, halogen atom, etc.; n is 1-3), etc.; R<5> represents 2-20C oxycarbonylalkyl; R<7> represents H or OH, provided that R<2>, R<4> and R<6> do not represent H at the same time] or salt thereof. EXAMPLE:2-Deoxy-2-[3R-(4-phenylbutanoyloxy)tetradecanoyl]amino-3-O-(4- phen ylbutanoyl)-4-O-sulfo-D-glucopyranose. USE:An immunological competence activator and an antitumor agent. PREPARATION:A compound expressed by formula VI is hydrolyzed under acidic condition.
申请公布号 JPS63179885(A) 申请公布日期 1988.07.23
申请号 JP19860287704 申请日期 1986.12.04
申请人 ONO PHARMACEUT CO LTD 发明人 TODA MASAAKI;SASAKI YUTARO;SHIMOJI KATSUICHI
分类号 C07D493/04;A61K31/35;A61K31/351;A61K31/70;A61K31/7024;A61K31/7028;A61P35/00;A61P37/00;A61P37/04;A61P43/00;C07D309/10;C07H13/06;C07H15/04;C07H15/18 主分类号 C07D493/04
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