PROSTAGLANDIN DERIVATIVES OF THE DELTA2,4-11-DEOXY-PEG SERIES

摘要

The present invention relates to novel prostaglandin derivatives of the formula I I which are structurally related to the naturally occurring prostaglandins and in which R1 denotes (a) hydrogen or a straight-chain or branched, saturated or unsaturated aliphatic or cycloaliphatic hydrocarbon radical having up to ten carbon atoms or (b) a physiologically acceptable metal or NH4 ion or an ammonium ion which is derived from a primary, secondary or tertiary amine and R2 denotes a straight-chain, aliphatic hydrocarbon radical having up to six carbon atoms and to a process for their manufacture. The compounds of the invention are distinguished in particular by gastric acid secretion-inhibiting and ulcer-protective properties.