| 摘要 |
The invention concerns novel racemic and optically active mono- and di-hydroxy alkanoic acids bearing phenyl and/or alkyl substituents, processes for their preparation, and pharmaceutical compositions for therapeutic use in the treatment of duodenal or gastric ulcers. Representative compounds of the invention are 2-(5 beta -n-butyl-4 beta -hydroxy-2-oxo-tetrahydrofuran-3 beta -yl)-2 alpha -methyl-acetic acid and 3 alpha -methyl-5 beta -(1 beta -hydroxy-n-pentyl)-2-oxo-tetrahydrofuran-4 beta -ylcarboxylic acid. |
