发明名称 Polyamide-fixed biologically active protein
摘要 Biologically active protein compositions comprising protein or a protein substrate bound onto a polyamide of the general formula: <IMAGE> in which R and R1, which may be the same or different, are polyamide residues bound onto the amido group, R2 is the residue of a compound which can be condensed with formaldehyde and which contains at least one further reactive group, R3 is the residue of a bi- or poly-functional protein reagent, n is 0 or 1, and P is a biologically active protein; these compositions are obtainable by the reaction of a polyamides with amounts, equimolar to one another, of formaldehyde and of a compound condensable with formaldehyde, in a solvent for polyamides, reacting the product thereby obtained with a bi- or poly-functional protein reagent and coupling the resulting reaction product with the biologically active protein or protein substrate.
申请公布号 US4182695(A) 申请公布日期 1980.01.08
申请号 US19780878545 申请日期 1978.02.16
申请人 BOEHRINGER MANNHEIM GMBH 发明人 ALBERT, WINFRIED;BATZ, HANS-GEORG;HORN, JURGEN;NELBOCK-HOCHSTETTER, MICHAEL
分类号 C08G69/00;C08G69/48;C08G69/50;C08H1/00;C12N11/08;(IPC1-7):A61K31/76;A61K31/77 主分类号 C08G69/00
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