1'-LOWER ALKYL-1'-(2-CYANO-METHYL)-1,2,3,4,6,7,12, 12B'-OCTAHYDRO-INDOLO -A)QUINOLIZINE COMPOUNDS

摘要

New compounds of the general formula (I) (I) wherein R stands for an alkyl group, have been prepared by reducing a compound of the general formula (II) (II) wherein R stands for an alkyl group of 1 to 6 carbon atoms, B stands for H2O or an X? anion derived from an acid, and if B is an X anion, A represents hydrogen, whereas if B is H2O, A represents an electron pair. If desired, the racemic compounds of the general formula (I) can be resolved to yield the corresponding optically active isomers. The free bases of the general formula (I) can be converted into their pharmaceutically acceptable salts, or the salts can be treated with an alkaline agent to yield the free bases. me compounds of the general formula (I) can be used primarily as vasodilatating agents.