摘要 |
2-(2-Chlorobenzyl)-1,2,3,4-tetrahydroisoquinoline of the formula <IMAGE> and its pharmaceutically acceptable addition salts, are useful for the treatment of arterial or venous thrombosis. They can be prepared by reducing the amide 2-(2-chlorobenzoyl)-1,2,3,4-tetrahydroisoquinoline, for example with boron hydride in an inert organic solvent, and optionally converting a free amine thereby produced into a salt. |