发明名称 PROCESS FOR PREPARING 3-ACYLOXYMETHYL-2-CEPHEM COMPOUNDS
摘要 <p>The present invention relates to a novel process whereby a 3-exomethylenecepham sulfoxide ester is reacted with a mixture of a C1-C4 carboxylic acid and a corresponding C1-C4 acid anhydride at a temperature of from about 70.degree.C. to about 130.degree.C. to produce the corresponding 3-acyloxymethyl-.DELTA.2-cephem, which is useful as an intermediate in the preparation of antibiotically active cephalosporins.</p>
申请公布号 CA1066268(A) 申请公布日期 1979.11.13
申请号 CA19760266534 申请日期 1976.11.25
申请人 ELI LILLY AND COMPANY 发明人 KOPPEL, GARY A.
分类号 A61K;C07C;C07D;C07D501/00;C07D501/04;C07D501/60;(IPC1-7):07D501/60 主分类号 A61K
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