| 摘要 |
This invention provides the beta -lactamase inhibitory compounds of the formula (II): <CHEM> and esters and acid addition salts of esters thereof wherein R<1> is an optionally substituted aromatic monocyclic or bicyclic heterocyclic group bonded via a carbon atom and R2 is a group CH2R1, a hydrogen atom, a C1-6 alkyl or hydroxyalkyl group, an optionally substituted benzyl group, or a group of the sub-formula (a): <CHEM> where Ra is a C1-3 alkyl group, and Rb and Rc are independently hydrogen, C1-3 alkyl or phenyl. The invention also relates to processes for their preparation and pharmaceutical compositions containing them. |
