Selective conversion of 20-methylpregna-3,5,20(21)-triene-3,21-diol-diacetate to 3-oxo-20-methylpregna-4,20(21)-diene-21-yl-acetate

摘要

{PG,1 The present invention relates to the conversion of 20-methylpregna-3,5,20(21)-triene-3,21-diol-diacetate to 3-oxo-20-methylpregna-4,20(21)-diene-21-yl-acetate through the use of a halogenated solvent and a halogenated acid. The benefits of the present invention include a substantial increase in the production of progesterone via ozonolysis technology.