| 摘要 |
During the aerobic fermentation process, when it is desired to kill the microorganism, a growth essential material such as the carbon source or the oxygen source is interrupted for a period of time sufficient to lower the concentration of the material to a level at which the microorganism substantially ceases to propagate. After this concentration has been reached, flow of the material is then rapidly reestablished in a quantity so that the concentration of the material in the fermentation medium is such that the microorganism will generate a toxic amount of formaldehyde and thereby kill the microorganism.
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