| 发明名称 |
FORFARANDE FOR FRAMSTELLNING AV 1,4-BENSODIOZEPINDERIVAT |
| 摘要 |
Benzodiazocines corresponding to the formula <IMAGE> are converted to benzodiazepines corresponding to the formula <IMAGE> of claim 1 by subjecting the benzodiazocine (a) if it is halogen-substituted in the 3-position to a thermal treatment which may also take place in the presence of a nucleophilic agent for the reaction or (b) if the 3-position is hydroxy substituted to treatment with a Lewis acid which is a chlorinating or brominating agent. Whenever the diazepine obtained as the final product has a 2-halogenomethyl group it may then be converted to benzodiazepine which is otherwise substituted in the 2-position. |
| 申请公布号 |
SE409709(B) |
申请公布日期 |
1979.09.03 |
| 申请号 |
SE19730006128 |
申请日期 |
1973.05.02 |
| 申请人 |
* KALI-CHEMIE AG |
发明人 |
W * MILKOWSKI;R * BUDDEN;S * FUNKE;R * HUSCHENS;H-G * LIEPMANN;W * STUHMER;H * ZEUGNER |
| 分类号 |
C07D317/66;A61K31/395;A61K31/55;A61K31/551;A61P25/00;A61P25/08;A61P25/20;A61P25/26;C07C;C07C67/00;C07C231/00;C07C231/02;C07C233/12;C07C233/78;C07C235/50;C07D;C07D243/14;C07D243/16;C07D243/28;C07D245/06;C07D319/18;C07D403/06;C07D405/02;C07D491/04;C07D491/056;(IPC1-7):07D243/16 |
主分类号 |
C07D317/66 |
| 代理机构 |
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代理人 |
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