摘要 |
<p>Conjugated ketone compounds of the formula: <IMAGE> wherein Ar is a naphthyl, furyl thienyl, or phenyl group optionally bearing one or more substituents selected from chlorine, bromine, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, trifluoromethyl and methylenedioxy, R1 is a C1-C6 alkyl, C3-C5 alkenyl, C3-C6 cycloalkyl, C7-C8 aralkyl or adamantyl group, R2 is a C1-C6 alkyl, C3-C5 alkenyl or C3-C6 cycloalkyl group or when R1 and R2 are taken together with the nitrogen atom to which they are attached, they form a heterocyclic amino group containing up to 8 carbon atoms and A is a straight or branched C1-C3 alkylene group, and their salts are useful as blood platelet anti-aggregative agents.</p> |