| 摘要 |
Process for the production of an ester product, 9-( beta -D-arabinofuranosyl)adenine, 5'-phosphate, in which the mixture resulting from reaction of 9-( beta -D-arabinofuranosyl)adenine with phosphorylating agent in trialkyl phosphate solvent is subjected to aqueous hydrolysis, the pH of the hydrolysis mixture is adjusted upward sufficiently to cause separation into aqueous and non-aqueous liquid phases, the trialkyl phosphate solvent is removed, and the product is precipitated from the residual aqueous mixture and isolated. |
