发明名称 |
Process for halogenation of aldehydes and production of oximes therefrom |
摘要 |
In the halogenation under reflux conditions of an unhalogenated aldehyde of the formula <IMAGE> with Cl2, Br2 or I2, the aldehyde and halogen are continuously fed into a reactor at a molar ratio of halogen to unhalogenated aldehyde between about 0.8:1 and about 1.1:1 and water is continuously fed into the unhalogenated reactor at a rate of between about 1% and about 20% by weight of aldehyde. The product alpha -haloaldehyde is thiohydrocarbylated and then oximated to form a 2-hydrocarbylthioaldoxime of the formula <IMAGE> with improved yield and quality because of the improved yield and quality of unhalogenated alpha -haloaldehyde. An exemplary process includes the chlorination of isobutyraldehyde (IBA) to form alpha -chloroisobutyraldehyde (CIBA), the thiomethylation of CIBA to form 2-methyl-2 methylthio-propionaldehyde (MTIBA) and the oximation of MTIBA to form 2-methylthio-propionaldehyde oxime (aldicarb oxime or ADO).
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申请公布号 |
US4155933(A) |
申请公布日期 |
1979.05.22 |
申请号 |
US19780894870 |
申请日期 |
1978.04.10 |
申请人 |
ALLIED CHEMICAL CORP |
发明人 |
BONFIELD, JOHN H;MURTHY, ANDIAPPAN K;PICKENS, DONALD |
分类号 |
C07C45/00;C07C45/63;C07C47/14;C07C67/00;C07C313/00;C07C319/20;C07C323/47;(IPC1-7):C07C131/00 |
主分类号 |
C07C45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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