发明名称 Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2{62 {0 side chain
摘要 The present invention encompasses compounds of the formula: <IMAGE> wherein n is 0 or 1; Y represents ethylene or vinylene; R represents hydrogen or lower alkyl having 1-7 carbon atoms; R', R'', R''' each individually represent hydrogen or methyl; Ar represents phenyl, halosubstituted phenyl, alkyl substituted phenyl wherein the alkyl contains 1-4 carbon atoms, alkoxy substituted phenyl wherein the alkoxy contains 1-4 carbon atoms, trifluoromethylphenyl, or biphenyl; and the wavy line indicates R or S stereochemistry.
申请公布号 US4149006(A) 申请公布日期 1979.04.10
申请号 US19770761567 申请日期 1977.01.24
申请人 G. D. SEARLE & CO. 发明人 COLLINS, PAUL W.;PAPPO, RAPHAEL
分类号 A61K31/20;A61K31/215;A61P15/00;A61P43/00;C07C43/23;C07C67/00;C07C401/00;C07C405/00;C07F7/18;(IPC1-7):C07C177/00 主分类号 A61K31/20
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