| 摘要 |
<p>The invention discloses novel compounds of the general formula: and salts thereof, in which X stands for oxygen, sulphur, the group ?NR7 or the group -CR8R9-; R1, R2, R3 and R4 represent hydrogen, hydroxy, halogen, alkyl (1-6 C), alkoxy (1-6 C), alkylthio (1-6 C) or trifluoromethyl; R5 and R6 represent hydrogen, alkyl (1-6 C), aralkyl (7-10 C) or together in combination with the nitrogen atom a heterocyclic five- or six-membered ring; R7 stands for hydrogen or alkyl (1-4 C); R8 and R9 stands for hydrogen or methyl, n is the number 0, 1 or 2 and the dotted line means an optional C-C bond, with valuable central nervous system (CNS) activities, especially antidepressant activity. The invention further discloses novel intermediates of the general formula: as well as biologically active intermediates of the formula: as well as salts and esters thereof.</p> |
