发明名称 THERAPEUTICALLY USEFUL MMTRIFLUOROOMETHYLPHENYLL PIPERADINE DERIVATIVE
摘要 Compounds of the formula I <IMAGE> wherein R1 represents a hydrogen or fluorine atom, and R2 represents an alkyl group containing 2 to 6 carbon atoms, or a cycloalkyl or cycloalkyl-alkyl group containing 5 to 8 carbon atoms, each of these groups being substituted by one or two hydroxy groups or an oxo group and, if desired, also by a 4-(m-trifluoromethylphenyl)-piperazino or 4-(3-trifluoromethyl-4-fluoro-phenyl)-piperazino group with the proviso that, when R1 represents a hydrogen atom, R2 does not represent a monohydroxyalkyl group, and their pharmaceutically acceptable acid addition salts are novel and have therapeutic use, notably in the region of the central nervous system and in the cardiovascular region.
申请公布号 JPS5439085(A) 申请公布日期 1979.03.24
申请号 JP19780001577 申请日期 1978.01.12
申请人 METABIO JOULLIE SA 发明人 MOORISU JIYURIE;GABURIERU MEIYAARU;RIYUSHIAN RAKA;KURISUCHIYAN JIYAN MARII WAROR;IBU ROBEERU ARAN PASUKARU
分类号 C07D295/06;A61K31/495;A61P11/14;A61P25/00;C07D295/088;C07D295/096;C07D295/10;C07D295/108;C07D295/116 主分类号 C07D295/06
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