发明名称 BENZIMIDAZOLE-2-DERIVATIVES.
摘要 <p>Novel substituted heterocyclyl compounds of the formula <IMAGE> (I) in which R is a free, esterified or amidated carboxyl group or a free, etherified or esterified hydroxymethyl group, R1 is an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclic-aliphatic radical, R2 is hydrogen or an aliphatic radical and Ph is a 1,2-phenylene group containing the radical R1-X, and X is lower alkylidene or a direct bond, and pharmaceutically usable salts of compounds of the formula I with salt-forming properties as medicaments, pharmaceutical preparations containing these, their use as medicaments and also novel compounds of the formula I and salts of compounds of the formula I with salt-forming properties, with the proviso that R1-X-Ph differs from 1,2-phenylene substituted by methyl in the 4- and/or 5-position when R is carboxyl, carbamyl or hydroxymethyl and R2 is hydrogen, and pharmaceutically acceptable salts thereof are useful as anti-allergic agents.</p>
申请公布号 IE781545(L) 申请公布日期 1979.02.01
申请号 IE19780001545 申请日期 1978.07.31
申请人 CIBA-GEIGY AG. 发明人
分类号 A61K31/415;A61K31/4184;A61P37/08;A61P43/00;C07C45/46;C07D235/12;C07D235/16;C07D235/24;C07D235/32;C07D405/02;(IPC1-7):C07D235/04 主分类号 A61K31/415
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