Disclosed is a method for treating and for preventing bone loss in patients by administering a formulation of 4-amino-1-hydroxy-butylidene-1,1-bisphophonic acid, disodium salt, or its hydrates. Also described is a pharmaceutical composition containing said disodium salt in a pharmaceutically acceptable excipient.
申请公布号
WO9639410(A1)
申请公布日期
1996.12.12
申请号
WO1996US08399
申请日期
1996.06.03
申请人
MERCK & CO., INC.;BRENNER, GERALD, S.;OBERHOLTZER, EARL, R., JR.;THIES, J., ERIC
发明人
BRENNER, GERALD, S.;OBERHOLTZER, EARL, R., JR.;THIES, J., ERIC