| 发明名称 |
METHOD OF PREPARING THE COMPLEX OF SILIBININE WITH CYCLODEXTRIN, INCLUSION COMPLEX OF SILIBININE WITH CYCLODEXTRIN, PHARMACEUTICAL COMPOSITION SHOWING ANTIHEPATOTOXIC ACTIVITY AND A METHOD OF ITS PREPARING |
| 摘要 |
FIELD: chemical-pharmaceutical industry. SUBSTANCE: invention relates to new complexes including silibinine with cyclodextrin and presented by groups consisting of alpha-,beta-,gamma--cyclodextrin and their corresponding derivative, and a method of their preparing. New complexes containing silibinine show enhanced biological activity as compared with silibinine and can be used in medicine for treatment of different hepatotoxic states. EFFECT: improved method of preparing, enhanced effectiveness. 5 cle
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| 申请公布号 |
RU2108109(C1) |
申请公布日期 |
1998.04.10 |
| 申请号 |
SU19914895027 |
申请日期 |
1991.03.28 |
| 申请人 |
MADAUS AG |
发明人 |
UMBERTO VALKAVI;VINTSENTSO MONTEROSSO;ROBERTO KAPONI;EHNRIKO BOZONE;VIL'FRID PETER VAKHTER;JOZHEF SEJTLI;UMBERTO VALKAVI;VINTSENTSO MONTEROSSO;ROBERTO KAPONI;EHNRIKO BOZONE;VIL'FRID PETER VAKHTER;JOZHEF SEJTLI |
| 分类号 |
A61K36/28;A61K;A61K9/00;A61K31/335;A61K31/35;A61K31/357;A61K31/70;A61K31/715;A61K31/724;A61K47/40;A61P1/16;C07D407/04;C08B37/16;(IPC1-7):A61K35/78 |
主分类号 |
A61K36/28 |
| 代理机构 |
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