| 发明名称 |
INCREASING METHOD FOR PRODUCTION OF SECONDARY METABOLITES USING CLUSTERED BIOSYNTHETIC GENE |
| 摘要 |
Clustered antibiotic biosynthetic genes are employed for improvement of production of the antibiotic in microorganisms and for the isolation of other genes involved in the biosynthesis of the antibiotic. The invention is exemplified with improved production of penicillin in Penicillium crysogenum, with the isolation of another clustered biosynthetic gene(s) and with the expression of penicillin biosynthetic genes in Acremonium chrysogenum. |
| 申请公布号 |
JPH02150284(A) |
申请公布日期 |
1990.06.08 |
| 申请号 |
JP19890209493 |
申请日期 |
1989.08.11 |
| 申请人 |
GIST BROCADES NV |
发明人 |
MARUTEINIYUSU ANTONIUSU MATEIRUDA GURUUNEN;ANNEMARII EBUERIIN FUEENSUTORA;PIETERU FUAN ZOORINGEN;BERUTEYUSU PIETERU KUUKUMAN;RUSHIA HERENA MARIA FUAN DERU FUOORUTO;FUAN FURANSHISUKO MARUTEIN;SANCHIAGO GUTSUTEIERURESU;BURUUNO DEIEESU;EMIRIO ARUBUAREESU;HOSE RUISU BARUREDO;KURISUCHIINA ESUMAAN |
| 分类号 |
C12N15/09;C07H21/04;C07K14/375;C12N1/15;C12N1/21;C12N9/00;C12N9/10;C12N9/52;C12N9/88;C12N15/10;C12N15/52;C12N15/80;C12P37/00;C12Q1/68;C12R1/04;C12R1/82 |
主分类号 |
C12N15/09 |
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