ETHYLENEIMINE INACTIVATED ORGANISMS

摘要

Microorganism can be rendered inactive without impairing their antigenicity or immunogenicity by treating the microorganism with ethyleneimine. The microorganism is placed in a suspension containing ethyleneimine up to a final concentration or 0.005% or 2% V/V. The temperature of the ethyleneimine-containing suspension is maintained between 0.degree. C and 45.degree. C for between a few hours and two days. The excess ethyleneimine is destroyed.