发明名称 2-Decarboxy-2-hydroxymethyl-{107 -phenyl-PGA or 9-deoxy-9,10-didehydro-PGD analogs
摘要 This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
申请公布号 US4107212(A) 申请公布日期 1978.08.15
申请号 US19770822033 申请日期 1977.08.05
申请人 THE UPJOHN COMPANY 发明人 NELSON, NORMAN A.
分类号 A61K31/045;A61K31/12;A61P43/00;C07C51/00;C07C57/30;C07C67/00;C07C401/00;C07C405/00;C07D263/04;C07D307/935;C07F9/40;C07F9/54;(IPC1-7):C07C49/82 主分类号 A61K31/045
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