摘要 |
<p>Antigenic virus materials, especially aqueous vaccines of all types in liquid or in freeze-dried form, are stabilized by incorporating therein at least 0.1% by weight of calcium lactobionate. Desirably 2-10% of lactose may also be incorporated and the vaccines of the invention are stated to retain their antigenicity at higher temperatures (e.g. at -20 DEG C. instead of -60 DEG C. for a measles vaccine) and to be able to withstand repeated freeze/thaw cycles. Other vaccines specifically mentioned are poliomyelitis, infectious hepatitis, yellow fever, mumps, rabies, smallpox and vaccinia vaccines.</p> |