发明名称 MULTILAYER MEMBRANE USEFUL AS SYNTHETIC SKIN
摘要 1518748 Multilayer membranes MASSACHUSETTS INSTITUTE OF TECHNOLOGY 8 July 1976] 15 July 1975] 28360/76 Heading B2E A multilayer membrane comprises a first layer formed from a cross linked polymer of collagen and a mucopolysaccharide, obtained by reacting collagen with the mucopolysaccharide, and cross linking the product wherein the polymer is cross linked to an M c value between 800 and 60,000 and contains at least 0.5 by weight of the mucopolysaccharide irreversibly bound to the collagen and a moisture transmission control layer formed from a non-toxic material, the control layer providing the multilayer membrane with a moisture flux of from 0.1-1 mg/cm<SP>2</SP>/hr. The mucopolysaccharide of the collagen-mucopolysaccharide composite may comprise a sulphate-containing mucopolysaccharide, e.g. chondroitin 6 - sulphate, chondroitin 4 - sulphate, heparin, heparan sulphate, keratan sulphate, or a dermatan sulphate. A moisture transmission control layer may be formed from a natural polymer or a synthetic polymer such as silicone resins, polyacrylate or polymethacrylate esters or polyurethane.
申请公布号 GB1518748(A) 申请公布日期 1978.07.26
申请号 GB19760028360 申请日期 1976.07.08
申请人 MASSACHUSETTS INSTITUTE OF TECHNOLOGY 发明人
分类号 B32B9/00;A61F2/00;A61F2/02;A61F2/10;A61L15/22;A61L27/00;A61L27/24;A61L33/10;B01D61/00;B01D71/08 主分类号 B32B9/00
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