发明名称 |
FREMGANGSMAATE TIL FREMSTILLING AV OPTISK AKTIVE 1,4-BENZDIAZEPIN-2-ON-DERIVATER |
摘要 |
<p>A process is disclosed for preparing optically active 1,4-diazepine-2-ones by reacting an acid chloride-hydrochloride of an optically active alpha -amino acid with a substituted o-amino benzophenone, to form an intermediate product and subsequently cyclizing the intermediate product to form the desired 1,4-diazepine-2-one. The process is carried out in inert organic or aqueous-organic solvents. The process eliminates the need for using alpha -amino acids having bound to the amino group a protective group which must be removed before cyclization.</p> |
申请公布号 |
NO137897(C) |
申请公布日期 |
1978.05.16 |
申请号 |
NO19740002739 |
申请日期 |
1974.07.29 |
申请人 |
CRC COMPAGNIA DE RICERCA CHIMICA S.A., |
发明人 |
KAJFEZ, FRANJO,;SUNJIC, VITOMIR, |
分类号 |
C07D243/14;C07D243/16;C07D243/18;C07D243/24;C07D243/28;C07D403/06;(IPC1-7):07D243/28 |
主分类号 |
C07D243/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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