摘要 |
<p>1507813 Citric acid PFIZER Inc 24 Jan 1977 [3 March 1976] 02800/77 Heading C2C Citric acid is prepared by a fermentation process using slack-wax as the principal source of assimilable carbon, with a yeast of genus Candida. The yeast is aerobically propagated using an aqueous nutrient containing an assimilable source of carbon to promote growth but insufficient to permit the accumulation of citric, e.g. glucose, a vegetable oil, a fatty acid ester or mixtures thereof, or a normal paraffin (9-19C), and conventional additives. The slack wax is added together with a solubilizing agent, e.g. alkanols (4-10C) alkyl esters of alkanoic acids (2-6C), alkenes, alkanes (8- 19C), turpentine, mineral oil and mixtures thereof and kerosene. Examples describe the use of n-octane, n-nonane, n-decane and ndodecane and turpentine, kerosene, mineral oil, butanol, amyl alcohol, octanol, decanol, ethyl acetate and butyl hexanoate as solubilizing agents.</p> |