| 摘要 |
<p>7-(Disubstituted-acetamido)-3-substituted-3-cephem-4-carboxylic acid and their process of preparation are provided of the formula wherein R1 is hydrogen, halogen, hydroxy, nitro, lower alkoxy or acylamino, R2 is hydrogen or acyl and R3 is lower alkanoyloxy, carbamoyloxy which may have lower alkyl, aryl or protective group for amino, or a heterocyclicthio which may have lower alkyl, and its derivatives at the carboxy group and pharmaceutically acceptable salts thereof; the novel compounds possess antibacterial activity and inhibit the growth of a number of microorganisms including Gram-positive and Gram-negative bacteria.</p> |
