| 摘要 |
Cephalosporins of the formula I in which R<1> represents alkyl having 1 - 4 C atoms and n is 1, 2 or 3, and non-toxic, pharmaceutically utilisable salts and esters thereof are obtained by reaction of an appropriate cephalosporin, which carries an acetoxymethyl group in the 3-position of the ring system, with an appropriate mercaptotetrazole compound. In an alternative process, this reaction is carried out using a cephalosporin having a free amino group, this being appropriately acylated in a second step. The compounds can be used in pharmaceutical compositions for the control of bacterial infections, such as Haemophilus or Neisseria infections. <IMAGE> |
