发明名称 Immunostimulant agent, compositions thereof and methods for their preparation
摘要 The immunostimulant agent is extracted from splenic cells of animal origin from Ehrlich ascites cells or from bacteria, such as Bacillus subtilis or Saccharomyces cerevisiae. A suspension of these cells or of these bacteria is formed with a mixture of solvents containing a halogenated hydrocarbon and an alcohol. The insoluble fractions are separated, the liquid fraction evaporated under reduced pressure and at reduced temperature, and the solid residue taken up again in chloroform. The chloroform solution containing the abovementioned immunostimulant agent is recovered by filtration. A suspension in an injectable liquid vehicle of the immunostimulant agent is in the form of particles or micelles whose dimensions are sufficiently small for said suspension to be injectable in man or animal.
申请公布号 US4076801(A) 申请公布日期 1978.02.28
申请号 US19750573925 申请日期 1975.05.02
申请人 INSTITUT PASTEUR 发明人 FAUVE, ROBERT
分类号 A61K35/28;A61K35/66;A61K39/39;(IPC1-7):A61K39/02;A61K39/04 主分类号 A61K35/28
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