发明名称 3-(1-HYDROXY-2-(HYDROXYPIPERIDINO)ETHYL)-5-PHENYISOXAZOLE
摘要 <p>3-[1-Hydroxy-2-(3- or 4-hydroxypiperidino)ethyl]-5-phenylisoxazole synthesized from 3-(1,2-epoxyethyl)-5-phenylisoxazole or 3-(1-hydroxy-2-active group-substituted ethyl)-5-phenylisoxazole with 3- or 4-hydroxypiperidine, or 3-(3- or 4-hydroxypiperidino)acetyl-5-phenylisoxazole or 3-(3- or 4-ketopiperidino)acetyl-5-phenylisoxazole by reduction showing strong analgesic and anti-inflammatory activities with low toxicity.</p>
申请公布号 CA1025867(A) 申请公布日期 1978.02.07
申请号 CA19740207367 申请日期 1974.08.20
申请人 SHIONOGI & CO., LTD. 发明人 TAKAHASHI, SHIRO
分类号 A61K;A61K31/41;A61K31/42;A61K31/435;A61K31/445;C07D;C07D211/40;C07D261/00;C07D261/08;C07D263/00;C07D413/06;(IPC1-7):07D413/06 主分类号 A61K
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