发明名称 (3)-Benzylidene-hydrazino-(1,2,4)-triazoles - useful as hypotensives without sedative side effects
摘要 <p>Triazole derivs. of formula (I) and their salts are new: (R1 and R2 are each H, NO2, alkyl, alkoxy, alkoxyalkyl or halo. R3 = H, alkyl, halo, alkoxy or NO2. n = 1 or 2). They are prepd. e.g. by reacting the appropriate benzaldehyde with 3-hydrazino-1,2,4-triazole. (I) have hypotensive activity and are free from sedative or other side-effects. The usual dose is 0.1-1 g./day orally or 5-40 mg./day intravenously. A specifically claimed cpd. is 3-(2,6-dimethylbenzylidenehydrazino)-1,2,4-triazole.</p>
申请公布号 FR2357549(A1) 申请公布日期 1978.02.03
申请号 FR19770020495 申请日期 1977.07.04
申请人 HASSLE AB 发明人 PEDER BERNHARD BERNTSSON, JAN ORNULF GAARDER ET BENGT RICHARD LJUNG;GAARDER JAN ORNULF;LJUNG BENGT RICHARD
分类号 A61K31/41;A61K31/4192;A61P9/12;C07D249/14;(IPC1-7):07D249/14;61K31/41 主分类号 A61K31/41
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