发明名称 |
Hydroxy acids |
摘要 |
The invention concerns novel racemic and optically active mono- and di-hydroxy alkanoic acids bearing phenyl and/or alkyl substituents, processes for their preparation, and pharmaceutical compositions for therapeutic use in the treatment of duodenal or gastric ulcers. Representative compounds of the invention are 2-(5 beta -n-butyl-4 beta -hydroxy-2-oxo-tetrahydrofuran-3 beta -yl)-2 alpha -methyl-acetic acid and 3 alpha -methyl-5 beta -(1 beta -hydroxy-n-pentyl)-2-oxo-tetrahydrofuran-4 beta -ylcarboxylic acid.
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申请公布号 |
US4070480(A) |
申请公布日期 |
1978.01.24 |
申请号 |
US19760716284 |
申请日期 |
1976.08.20 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES LIMITED |
发明人 |
ALDRIDGE, DAVID CECIL;CRAWLEY, GRAHAM CHARLES;STRAWSON, COLIN JOHN |
分类号 |
A61K31/19;A61K31/365;A61P1/04;C07C51/00;C07C51/09;C07C59/01;C07C59/285;C07C59/42;C07C67/00;C07C69/675;C07D307/33;(IPC1-7):C07D307/32;C01B15/12 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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