FORFARANDE FOR FRAMSTELLNING AV 2,4,5,6-TETRAHYDROCYKLOPENTA/C/PURROL-4-KARBOXAMIDER OCH -4-TIOKARBOXAMIDER MED TERAPEUTISK VERKAN

摘要

2,4,5,6-Tetrahydrocyclopenta[c]pyrrole-4-carboxamide and 4-thiocarboxamide derivatives useful as antisecretory and anti-ulcer agents are prepared by hydrolysis or thiohydrolysis of the corresponding 2,4,5,6-tetrahydrocyclopenta[c]pyrrole-4-carbonitriles or, in the case of the thiocarboxamides, by reaction of the 4-carboxamide with phosphorus pentasulfide.