MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF OXOALKYLXANTHINES

摘要

Title cpds. of formula (I) (where >=1 of R1-R3 = 3-8C oxoalkyl with the CO gp(s) one or more C's removed from the xanthine nucleus, and the others are 1-6C alkyl). may be prepd. from the corresp. hydroxy alkyl cpds. by (a) dehydrogenation with O2 and a Gp VIII metal catalyst. (b) oxidation with Cr(VI), or (c) microbiological dehydrogenation.