| 摘要 |
Compounds of the formula I <IMAGE> wherein A is hydrogen, hydroxy, methyl or methoxy, R1 is hydrogen, sodium or potassium, R2 is carboxyl or 2-furyl or an aliphatic, aromatic or heterocyclic radical to which there is also attached a strongly acidic group in the form of its sodium or potassium salt, and R3 is tetrazol-5-yl, 1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-2-yl, 1,3,4-oxadiazol-3-yl or 1,2,4-triazol-5-yl, each of such groups being unsubstituted or substituted with one or two lower alkyl groups of one to four carbon atoms are prepared by reacting the appropriate aldehyde with the corresponding amphoteric cephalosporin. Preferred products have the structure <IMAGE> +tr <IMAGE> in which A is -H or -SO3Na.
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