发明名称 BIS-BIGUANIDE COMPOUNDS
摘要 The composition for oral and/or dental care contains a vehicle for use in the oral cavity and antiplaque agent of the formula (1) <IMAGE> in which A and A' are each a substituted phenyl radical with halogen atoms, nitro or hydroxyl groups, alkyl radicals with 1 to 6 C atoms or alkoxy radicals with 1 to 6 C atoms as substituents, X and X' are each an alkylene radical with 1 to 3 C atoms and z and z' are each zero or one, R and R' are each hydrogen atoms, alkyl radicals with 1 to 12 C atoms or aralkyl radicals with 7 to 12 C atoms, R2 and R2' are each hydrogen atoms or alkyl radicals with 1 to 2 C atoms, and n is a number from 1 to 4, or a pharmacologically acceptable salt of an antiplaque agent of the formula (1) and is virtually free of metal ion chelating agents and of substances which form insoluble salts with the antiplaque agent.
申请公布号 AU1458476(A) 申请公布日期 1977.12.08
申请号 AU19760014584 申请日期 1976.06.03
申请人 PROCTER & GAMBLE CO. 发明人 PREM SAGAR JUNEJA
分类号 A61K31/155;A61K8/43;A61K31/047;A61P1/02;A61Q11/00;C07C67/00;C07C239/00;C07C279/26 主分类号 A61K31/155
代理机构 代理人
主权项
地址