发明名称 Prostaglandin analogues
摘要 Prostaglandin compounds of the formula: <IMAGE> VII wherein A represents a grouping of formula II, III or IV indicated below and (i)R1 represents an unsubstituted n-butyl, n-pentyl, n-hexyl or n-heptyl radical, or such a radical carrying one, two or three alkyl substituents of 1 to 4 carbon atoms, or R1 represents a methyl, ethyl, propyl or butyl radical carrying a phenyl, cyclohexyl or cyclopentyl substituent, R2 represents a hydrogen atom or an alkyl radical of 1 to 4 carbon atoms, and R3 represents a hydrogen atom, or (ii) R1 represents n-butyl, or n-butyl or n-pentyl carrying one, two or three alkyl substituents of 1 to 4 carbon atoms, or R1 represents a methyl, ethyl, propyl or butyl radical carrying a phenyl, cyclohexyl or cyclopentyl substituent, R2 represents a hydrogen atom or an alkyl radical of 1 to 4 carbon atoms, and R3 represents an alkyl radical of 1 to 4 carbon atoms are disclosed. These compounds exhibit characteristic prostaglandin-like activity.
申请公布号 US4061865(A) 申请公布日期 1977.12.06
申请号 US19750603475 申请日期 1975.08.11
申请人 ONO PHARMACEUTICAL COMPANY 发明人 HAYASHI, MASAKI;TANOUCHI, TADAO;ITO, HIROYUKI;OHYAMA, ISAO
分类号 C07C405/00;C07D307/935;(IPC1-7):C07C177/00 主分类号 C07C405/00
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