发明名称 |
DEAMINOODERIVATIVE OF KALLIKREINNTRYPSIN INHIBITOR AND ITS PRODUCTION AND MEDICAL APPLICATION |
摘要 |
A demaino kallikrein-trypsin inhibitor obtained from cattle organs is characterized by (a) 0 to 3 lysine residues and/or 3 to 6 arginine residues and/or 1 to 4 tyrosine residues; (b) the 10- and/or 21-tyrosine residues being unsubstituted or substituted by at least one nitro, nitroso or amino in the ortho position relative to the phenolic hydroxy group; and (c) having protease inhibitory activity of BPTI and elastase inhibition activity. |
申请公布号 |
JPS52134009(A) |
申请公布日期 |
1977.11.09 |
申请号 |
JP19770048597 |
申请日期 |
1977.04.28 |
申请人 |
BAYER AG |
发明人 |
OIGEN SHIYUNAABERU;HORUSUTO DEIITAA SHIYURUMUBERU;GERUTO RAINHARUTO;ERUNSUTO TORUSHIYAITO;HARARUTO CHIESHIE |
分类号 |
A61K35/12;A61K38/00;A61K38/55;A61P3/00;A61P29/00;A61P37/00;A61P43/00;C07K14/81 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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