WERKWIJZE VOOR HET BEREIDEN VAN DESAMINODERIVATEN VAN DE CALLICREINE-TRYPSINE-INHIBITOR, ALSMEDE TOEPASSEN VAN DEZE DESAMINODERIVATEN ALS GENEES- MIDDEL.

摘要

A demaino kallikrein-trypsin inhibitor obtained from cattle organs is characterized by (a) 0 to 3 lysine residues and/or 3 to 6 arginine residues and/or 1 to 4 tyrosine residues; (b) the 10- and/or 21-tyrosine residues being unsubstituted or substituted by at least one nitro, nitroso or amino in the ortho position relative to the phenolic hydroxy group; and (c) having protease inhibitory activity of BPTI and elastase inhibition activity.