摘要 |
<p>1409936 Prostaglandins ROUSSEL UCLAF 23 Nov 1973 [23 Nov 1972] 54533/73 Heading C2C Novel compounds of Formula I (in which R=H or C 1-4 alkyl, R 1 = H or C 1-2 alkyl, R 2 = H orα-tetrahydropyranyl, m = 3, 4 or 5 and n=2, 3 or 4) and the base salts of those compounds in which R = H, are prepared by reacting a compound of Formula II with a compound of formula and, if desired, converting a resulting compound I in which R = H into a base salt. Pharmaceutical compositions having hypotensive, smooth muscle contracting, antibron - choconstrictive and antilipolytic activity, for oral, parenteral, rectal or topical administration, comprise one of the above novel compounds together with one or more pharmaceutical carriers or excipients. The compositions may also be in an aerosol form.</p> |