HYDROPHOBIC SUBSTRATES HAVING GRAFTED HYDROPHILIC INCLUSIONS CONTAINING POLAR SOLUBLE SUBSTANCES

摘要

1486288 Sustained release of medicaments COMMISSARIAT A L'ENERGIE ATOMIQUE 4 Nov 1974 [9 Nov 1973] 47545/74 Heading A5B [Also in Division C3] A hydrophobic polymeric substrate has cross-linked polymerised hydrophilic inclusions derived from an hydrophilic ethylenically unsaturated monomer grafted to the substrate and distributed throughout the volume thereof and has a medicament, soluble in polar solvents, stored in said inclusions and desorbable therefrom on contacting the hydrophobic polymeric substrate with a polar solvent.