| 发明名称 |
Process for resolving alanine, 3-fluoro and 2-deutero-3-fluoro-DL-alanine |
| 摘要 |
DL-Alanine, 3-fluoro-DL-alanine and 2-deutero-3-fluoro-DL-alanine, are resolved by reaction with a resolving base and a beta -dicarbonyl compound. The resulting azomethine diastereomeric salts which are easily separated, the masking group is readily removed under mildly acidic conditions.
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| 申请公布号 |
US4048224(A) |
申请公布日期 |
1977.09.13 |
| 申请号 |
US19760664328 |
申请日期 |
1976.03.05 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
CHEMERDA, JOHN M.;GAL, GEORGE |
| 分类号 |
C07C227/34;A61K31/195;A61K31/198;A61P31/04;C07C;C07C67/00;C07C227/00;C07C227/06;C07C227/36;C07C227/40;C07C229/08;C07C229/20;(IPC1-7):C07C101/10;A61K31/19 |
主分类号 |
C07C227/34 |
| 代理机构 |
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