发明名称 Composition for antagonizing the narcotic effects of barbiturate addiction and withdrawal effects, and for treatment of barbiturate poisoning
摘要 The invention is based on the discovery, after long study and many test operations, that the combination of five chemical elements, towit 5-hydroxymethylcytosine, thymine, nicotamide, pyridoxal, and thiamine, is effective in antagonizing the narcotic effects of barbiturates, and that each one is essential, in the combination, for positive result. Although thymine per se long has been known as increasing the action of barbiturates, tests of the said composition established that thymine has an unexpected and essential function therein, its omission rendering the composition ineffective. These tests were directly made by the present applicant, with corroboration as to every detail thereof by the Chief of the Section of Neurochemistry, New York State Institute of Neurochemistry and Drug Addiction, established by the State of New York, and operating under its control.
申请公布号 US4048316(A) 申请公布日期 1977.09.13
申请号 US19740447659 申请日期 1974.03.04
申请人 PENN, NATHAR W. 发明人 PENN, NATHAR W.
分类号 A61K31/51;(IPC1-7):A61K31/50 主分类号 A61K31/51
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