| 摘要 |
Anti-allergic agents of N-aromatic and N-heterocyclic 1H-(or 2H) tetrazole-5-carboxamide derivation present the following formulae: <IMAGE> in which A is a member selected from the group consisting of 2-thiazolyl, 2-pyridyl, 6-(lower)alkyl-2-pyridyl, 3-cyano-2-pyridyl, 3-pyridyl, 4-pyridyl, 2-pyrimidinyl, 2-pyrazinyl, alpha -naphthyl, beta -naphthyl, phenyl, 2,6-dichlorophenyl, and substituted phenyl moieties containing from one to three substituents in any of the 2, 3, 4 and 5 positions of the phenyl ring, independently selected from the group consisting of lower alkyl, lower alkylsulfinyl, lower alkoxy, hydroxy(lower)alkoxy, 2-(lower alkoxy oxalyloxy)ethoxy, N-mono- and di-lower alkylamino(lower)-alkoxy, sulfamyl, polyhalo(lower)alkyl, carbamyl, N-lower alkylcarbamyl, mono- and di- lower alkylamino, carboxy, lower alkylcarbonyl, cyano, carb(lower)alkoxy, phenoxy(lower)alkoxy, lower alkoxyoxalamido and lower alkoxyoxalamidophenoxy radicals; AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF.
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