PREPARATION OF PROSTAGLANDINNLIKE COMPOUNDS

摘要

PURPOSE:Prostaglandin-like compounds of formula I [Z<1> is (protected) COOH; Z<2> is (protected) COOH; Z<3> is hydroxymethyl which may have protective group; Z<4> is H, (substd.) alkyl; Z<5> is H, alkyl; dotted lines represent alpha-configuration]; for example, (5Z, 9alpha, 11alpha, 13E, 15R)-9, 15-dihydroxy-11hydroxymethyl-12-isoprosta-5,13-dien-1-oic acid.