BETA-LACTAM ANTIBIOTIC COMPOUNDS THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

beta -Lactams of the formula AND PHARMACEUTICALLY ACCEPTABLE NONTOXIC SALTS THEREOF WHEREIN A is hydrogen or alkyl of 1 to 4 carbon atoms; B is phenyl, methylphenyl, chlorophenyl, hydroxyphenyl or cyclohexa-1,4-dien-1-yl; R is a moiety of the formula WHEREIN E is hydrogen -OH or -O- CO-CH3; and C constitutes a center of chirality; are produced which exhibit antibiotic activity.