| 摘要 |
Novel 1-substituted-4-benzylidene piperidines useful as antiinflammatory agents and tranquilizers are represented by the formula WHEREIN R represents acetyl, aryloxyloweralkyl, aroylloweralkyl, carbamoyl, N-lower-alkylcarbamoyl, N,N-dilower-alkylcarbamoyl, N-arylcarbamoyl or 2-hydroxy-3-(o-methoxyphenoxy)propyloxycarbonyl; R1 represents phenyl, p-fluorophenyl, m-trifluoromethylphenyl or cyclohexyl; Y represents hydrogen or fluorine with the proviso that when Y is hydrogen and R1 is phenyl, R is other than aroylloweralkyl. The pharmaceutically acceptable acid addition salts of the basic compounds of Formula I are included as part of the invention. |
